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Author: Josh

  • Philosophy: “Torture is wrong”

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    inspired from: https://www.meetup.com/think-and-drink-cambridge/events/308632835/ What Does It Mean to Say “Torture Is Wrong”? A Philosophical Excavation The assertion “torture is wrong” seems, at first blush, to carry the weight of moral certainty, as though it were a self-evident truth etched into the fabric of human conscience. Yet, when we pause to interrogate this statement, its clarity…

  • AI: Radical resolution

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    (This is meant as a light-hearted take on superresolution!) Super-resolution—the process of reconstructing high-resolution images from low-resolution inputs—is a foundational technology in modern computational imaging. From revealing microscopic structures in biomedical scans to clarifying satellite images from orbit, super-resolution techniques serve as critical tools in medicine, science, defense, and digital media. Traditional methods, such as…

  • Mythology: Legends of Moana

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    When Moana sailed into theaters in 2016, audiences were captivated not just by its vibrant animation and memorable music, but by its rich tapestry of mythology and legend drawn from the cultures of Polynesia. The film is more than a coming-of-age tale—it is a homage to the vast oceanic civilizations that span the Pacific Islands,…

  • Science: Iron in the ocean

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    In the vast, seemingly boundless stretches of the open ocean—especially the oligotrophic gyres and high-nutrient, low-chlorophyll (HNLC) regions—life is surprisingly dependent on a microscopic trace metal: iron (Fe). Though abundant in the Earth’s crust, iron is exceedingly scarce in seawater. And yet, it plays an outsized role in marine ecosystems, regulating biological productivity, influencing atmospheric…

  • MRI: Cryogen free tech

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    New Cryogen-Free Technology for Achieving Superconductivity Cryogen-free technology for superconductivity refers to systems that achieve and maintain the low temperatures required for superconducting states without relying on traditional cryogenic liquids like liquid helium (boiling point ~4.2 K) or liquid nitrogen (boiling point ~77 K). Instead, these systems use closed-cycle cryocoolers, such as pulse tube cryocoolers…

  • MRI: Quantum coherence

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    Multiple quantum coherence (MQC) is a central concept in nuclear magnetic resonance (NMR) spectroscopy, describing the correlated evolution of multiple nuclear spins in a quantum mechanical system. It plays a critical role in advanced NMR experiments, enabling the study of molecular structure, dynamics, and interactions with high resolution and sensitivity. Below, I provide a comprehensive…

  • MRI: Nuclear Overhauser Effect

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    The Nuclear Overhauser Effect (NOE) is a fundamental phenomenon in nuclear magnetic resonance (NMR) spectroscopy, widely used to probe the spatial proximity and dynamics of nuclear spins in molecules, particularly in structural biology and organic chemistry. Below, I provide a comprehensive description of the NOE, including its physics, chemistry, pulse sequences, and applications, as requested.…

  • Health: Prostate cancer

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    Prostate cancer is a biologically heterogeneous disease that affects the prostate gland, a small gland in males located below the bladder and in front of the rectum. The prostate plays a critical role in producing seminal fluid. Prostate cancer can range from slow-growing tumors that may never cause symptoms or require treatment, to highly aggressive…

  • Science: Tropical flowers and fragrance

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    The smells of tropical versus non-tropical (temperate and other climate zone) flowers differ significantly in intensity, composition, and ecological function, shaped by evolutionary pressures, pollinator availability, and environmental conditions. This in-depth comparison explores the biology, chemistry, and ecological roles behind floral scents across climate zones. 🌺 TROPICAL FLOWERS: SCENT CHARACTERISTICS AND ECOLOGICAL CONTEXT 1. Do…

  • Imaging: Carbon-13

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    Hyperpolarized carbon-13 magnetic resonance imaging (HP ^13C MRI) is an advanced imaging modality that significantly enhances the magnetic resonance signal of ^13C-labeled compounds, enabling real-time visualization of metabolic processes in vivo. This technique has profound implications for diagnosing and monitoring various diseases, including cancer, cardiovascular conditions, and inflammatory disorders.Wiley Online Library+4PubMed+4PMC+4Analytical Science Journals+2PMC+2braintumorcenter.ucsf.edu+2 Dynamic Nuclear…