Author: Josh
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Bitcoin: Satoshi candidates, and why they aren’t
The advent of Bitcoin in 2009 marked a paradigm shift in the realm of digital finance, introducing a decentralized cryptocurrency that operates without the need for traditional financial intermediaries. Conceived by an enigmatic figure known only as Satoshi Nakamoto, Bitcoin has not only revolutionized how we perceive and interact with money but has also spawned…
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History: Pre-Civilisation
I. Introduction: Setting the Stage for Humanity’s Deep History (200,000 BCE – 5000 BCE) The narrative of human history extends far beyond the advent of recorded events, stretching back into the vast epochs of prehistory. This report delves into a critical period of this deep history, spanning from approximately 200,000 BCE to 5000 BCE. This…
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Science: Genetics
1. Foundations of Genetics: The field of genetics is fundamentally concerned with understanding heredity, the process by which parents transmit specific traits to their offspring 1. This discipline delves into the intricacies of how these traits are passed from one generation to the next, focusing particularly on genes as the basic units responsible for this…
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Science: Inflammation
The immune system represents a sophisticated and multifaceted network of organs, cells, and proteins dedicated to defending the body against a constant barrage of infectious agents while meticulously safeguarding the integrity of the body’s own cells 1. This intricate defense mechanism possesses a remarkable ability to not only neutralize immediate threats but also to retain…
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Academic Culture: Inclusion in Hospital Research
The increasing recognition of the importance of Equity, Diversity, and Inclusion (EDI) has permeated various sectors, and research is no exception. Within the realm of scientific inquiry, fostering environments where individuals from all backgrounds can thrive and contribute meaningfully is not merely an ethical imperative but also a catalyst for innovation and progress. This report…
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Science: Health Economics of Medical Imaging
Introduction: The Evolving Landscape of Medical Imaging and Health Economics Health economics, as an applied field of study, provides a systematic and rigorous framework for examining the challenges inherent in promoting health for all . It applies economic theories related to consumer, producer, and social choices to understand the behavior of individuals, healthcare providers, organizations,…
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Science: Monoclonal Antibodies
Monoclonal antibodies (mAbs) are laboratory-made molecules that can bind to specific targets in the body. They are designed to mimic the immune system’s ability to fight off harmful pathogens like viruses or bacteria, but they are engineered to target particular proteins or molecules. Here’s a breakdown of how they’re useful for imaging and drug delivery:…
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Philosophy: What is beauty?
The question of what constitutes beauty has captivated thinkers for millennia, standing as a cornerstone of aesthetic philosophy and a subject of perpetual debate . This seemingly simple inquiry unravels into a complex tapestry of perspectives, marked by fundamental disagreements, particularly concerning whether beauty resides in the object itself or in the eye of the…
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History: The Ides of March
The Ides of March—March 15, 44 BCE—stands as one of history’s most infamous dates, immortalized by the brutal assassination of Julius Caesar. Far from a mere historical footnote, this event is a cauldron of controversy, simmering with questions about power, betrayal, and the ethics of political violence. Was Caesar a tyrant who deserved his fate,…
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USA: Trump’s Science Cuts
The Trump administration’s second term has been characterized by a bold and aggressive push to reduce federal funding for scientific research, a policy direction significantly shaped by Elon Musk’s influence through the newly established Department of Government Efficiency (DOGE). This initiative, aimed at slashing government expenditure and enhancing operational efficiency, has targeted major scientific agencies…